A 2 to 4-week-old puppy feeding schedule should consist of feedings every 6 to 8 hours.Newborn puppies need to eat every 2 to 3 hours, but as long as they get four to five full-sized meals in the course of the day, nighttime feedings are generally not necessary.Put a finger against the puppy’s throat to feel if they are still swallowing. Continue feeding until the puppy’s suckling stops or slows dramatically.Tip the bottle so that any air inside stays away from the nipple. Place the pup on your lap or on a towel on a table and insert the nipple into their mouth. Puppies are best fed in a belly-down position.Test the nipple before every feeding to ensure that milk only drips from the opening.Warm the bottle by placing it in a cup of hot water until the milk reaches body temperature.Reconstitute powdered milk replacer per label instructions or use a premixed variety.You’ll also need several pet nurser bottles as well as a variety of nipples. Milk replacers designed specifically for puppies is the best alternative to mother’s milk.But bottle feeding the wrong thing, the wrong way, the wrong amount or on the wrong schedule can lead to illness or even death. There are times, however, when bottle feeding puppies becomes necessary (such as when a pup is orphaned). Whenever possible, puppies should be nursed and raised by their mothers. If a puppy loses weight or fails to gain, contact your veterinarian. While a pup may not gain weight the first day (a healthy starting weight is different for each breed and can be determined by your veterinarian), there should be steady weight gains after that. (Don’t substitute a kitten or human formula.) If you are raising puppies yourself without the mother, or you need to supplement puppies for another reason, a formula specifically made for puppies is the best option. The best puppy food for your puppy’s first month of life is their mother’s milk, which has the best balance of nutrients for a growing puppy. Feeding Puppies From Birth Through 4 Weeks of Age